Abstract : Eating disorders ED affect a large population and are a serious public health issue. It is thus essential to deepen our knowledge of ED pathophysiology in order to open new therapeutic perspectives.
The prevalence of ED according to sex, geographical origin or age of the study population and its increase over the last 15 years has been highlighted in a systematic review. These comorbidities were strongly associated with each other, and contributed in a vicious circle to the perpetuation of ED. The literature suggests during ED a dysregulation of neuropeptide signaling of food intake that may include some immunological mechanisms.
Analyzes of plasma samples from the EDILS cohort allowed a better definition of the peptides and immunoglobulins profiles associated with the 3 broad categories of ED and to evaluate their utility for phenotyping patients.
The collection of feces in the cohort offers the possibility of refining the specificity of the microbiota according to different type of ED. This thesis allows to better define the clinical characteristics of 3 broad categories of ED and disturbances of the microbiota-intestine-brain axis, particularly the associated biological dysregulations of neuropeptide signaling. Document type : Theses. O pen R epository and Bi bliography. You are here: ORBi Detailled reference.
Sartre From a phenomenological perspective, anorexic patients seem to experience difficulties regarding the subjective feeling of their own body embodiment and their personal identity, which leads to an inter-subjectivity impairment within social interactions.
These patients were expected to define themselves mostly through the eyes of others instead of from their own perspective: their Leib i. Hypothesis: The main hypothesis assumed that anorexic patients would define themselves mostly through the eyes of others and would tend to experience less bodily sensations than control participants. Significant higher scores for these dimensions in the clinical group compared to the control group were expected. Method: this study included 67 anorexic female patients based on the Diagnostic and Statistical Manual IV criteria and control female participants.
All the participants were French speakers from Belgium, France and Switzerland.
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